ATLAS‑LRO Nexus
A Living Research Operating System
The problem
A research paper is a static description of work nobody else can re-run. Its claims cannot be queried, its methods cannot be executed, and its provenance is a log file — which is why reproducing published science is so expensive, and why regulators cannot simply trust it.
What we built
A platform that compiles a paper into a Living Research Object: queryable claims with mandatory citations, a causal graph for counterfactual reasoning, methods that execute in sandboxed containers, and a cryptographic ledger that makes provenance verifiable rather than asserted.
Why it matters
A paper becomes a callable function. You can ask what happens at a different dose, compose one paper's method with another's, and hand a regulator an audit trail that cannot be quietly edited.
Engineering highlights
- Executable method runtime — pinned images, data and seeds, replayable byte-for-byte, with author-bounded parameter sweeps
- Causal engine — do-calculus over a causal graph, not similarity search dressed up as reasoning
- Cryptographic provenance ledger — tamper-evident and regulator-ready
- Federated knowledge mesh — cross-publisher truth layer, controversy detection and an LRO exchange
- Deployment-profile architecture — runs from a single-node pilot up to a full Kubernetes install; add services as you add capability
- Compliance-aware — SOC 2 Type I control mapping, HIPAA technical safeguards, FDA/EMA/ICH narrative engine
Stack
- 20+ microservices
- FastAPI
- Next.js
- TypeScript
- Temporal
- PostgreSQL
- pgvector
- Neo4j
- Kafka
- MinIO
- Docker
- Helm
- Kubernetes
- Python / TS / CLI SDKs
Database-agnostic storage, provider-agnostic inference and pluggable extension points throughout — no component assumes a single vendor.